The use of Reishi as an herbal remedy dates back longer than any other medicinal mushroom in historic literature. The first written record can be found in Shen Nong's Herbal Classic, dating back two thousand years. Reishi (a.k.a. Ganoderma or Ling Zhi) is often considered a panacea " cure-all " in Traditional Chinese Medicine. While it may not be literally accurate to refer to Reishi as a cure-all, the fact that it appears to act as an inflammation modulator may be one of many reasons for its age-old veneration in the Orient.
In fact, Chinese medical practitioners have been prescribing Reishi extract for ages in cases of arthritis, bronchitis and other conditions involving any type of inflammation. Modern research in Asia as well as in America and Europe confirm the validity of these uses. Out of 19 papers used for this article, 17 reported positive results in the use or Reishi extract for arthritis. Only two were studies were inconclusive, both of which were conducted by the same research team. (1,2)
Regarding anti-inflammatory properties in general, a study out of India (2003) demonstrated that Reishi decreased inflammation in cases of acute or chronic edema by 56% and 60% respectively. (3) An earlier American study (1993) had already shown that, water extracts of G. pentaphyllum and G. lucidum [Reishi] were found to possess significant anti-inflammatory activity. (4) In the references are seven additional papers listed which all conclude that Reishi (Ganoderma lucidum) possesses potent anti-inflammatory qualities. (5,6,7,8,9,10,11)
Next we'll be looking at some studies that more directly relate to the use of Reishi extract with arthritis. A paper published in 2006 by Blum et al. claimed to provide supporting clinical evidence demonstrating that use of Reishi extract for joint health was both safe and effective. (12)
Also in 2006, a paper by Xi Bao et al. concluded that Reishi in conjunction with another Chinese herbal remedy might exert a beneficial immunomodulatory effect in patients with rheumatoid arthritis. (13)
The answer as to how, precisely, Reishi extract accomplishes this "immunomodulatory effect" may have been given by another Chinese study the following year, which states that an isolated Reishi polysaccharide peptide "significantly inhibited" RASF, which is an indicator of rheumatoid arthritis. (RASF stands for "Rheumatoid Arthritis Synovial Fibroblasts.") (14)
Several additional papers have been published that summarize positive results in the use of Reishi against arthritis. (15,16,17) One even states that Reishi compares favorably to prednisone, albeit without side effects. (18) On the other hand, a separate study found that supplementing with Reishi helped balance the side effects of prednisolone* that were experienced by some patients, including protein in the urine and cell toxicity. (19) (Prednisolone is the active compound of prednisone, which gets broken down by the liver and converted to prednisolone.)
In conclusion, the findings of 17 out of the 19 scientific papers referenced for this article agree that Reishi can help support joint health in cases of arthritis. However, it is important to always consult a licensed medical practitioner before using any herb for medicinal purposes, and to never change the use of existing prescription drugs without talking to your doctor about it first.
Name clarification: The Japanese name Reishi includes many closely related species. By far the most prevalent is Ganoderma lucidum (Common Reishi or Red Reishi), a species rare in the U.S. but common in South East Asia. The English common name for Ganoderma lucidum is Varnished Conk. In China, its known as Ling Zhi.
Other species frequently referred to as Reishi include: Ganoderma tsugae (Hemlock Reishi, common on Hemlocks in Eastern U.S.), Ganoderma sinense ("Black Reishi), Ganoderma resinaceum (Red Reishi), Ganoderma japonicum (Purple Reishi) and Ganoderma neo-japonicum (no common name or simply Reishi). - 30414
In fact, Chinese medical practitioners have been prescribing Reishi extract for ages in cases of arthritis, bronchitis and other conditions involving any type of inflammation. Modern research in Asia as well as in America and Europe confirm the validity of these uses. Out of 19 papers used for this article, 17 reported positive results in the use or Reishi extract for arthritis. Only two were studies were inconclusive, both of which were conducted by the same research team. (1,2)
Regarding anti-inflammatory properties in general, a study out of India (2003) demonstrated that Reishi decreased inflammation in cases of acute or chronic edema by 56% and 60% respectively. (3) An earlier American study (1993) had already shown that, water extracts of G. pentaphyllum and G. lucidum [Reishi] were found to possess significant anti-inflammatory activity. (4) In the references are seven additional papers listed which all conclude that Reishi (Ganoderma lucidum) possesses potent anti-inflammatory qualities. (5,6,7,8,9,10,11)
Next we'll be looking at some studies that more directly relate to the use of Reishi extract with arthritis. A paper published in 2006 by Blum et al. claimed to provide supporting clinical evidence demonstrating that use of Reishi extract for joint health was both safe and effective. (12)
Also in 2006, a paper by Xi Bao et al. concluded that Reishi in conjunction with another Chinese herbal remedy might exert a beneficial immunomodulatory effect in patients with rheumatoid arthritis. (13)
The answer as to how, precisely, Reishi extract accomplishes this "immunomodulatory effect" may have been given by another Chinese study the following year, which states that an isolated Reishi polysaccharide peptide "significantly inhibited" RASF, which is an indicator of rheumatoid arthritis. (RASF stands for "Rheumatoid Arthritis Synovial Fibroblasts.") (14)
Several additional papers have been published that summarize positive results in the use of Reishi against arthritis. (15,16,17) One even states that Reishi compares favorably to prednisone, albeit without side effects. (18) On the other hand, a separate study found that supplementing with Reishi helped balance the side effects of prednisolone* that were experienced by some patients, including protein in the urine and cell toxicity. (19) (Prednisolone is the active compound of prednisone, which gets broken down by the liver and converted to prednisolone.)
In conclusion, the findings of 17 out of the 19 scientific papers referenced for this article agree that Reishi can help support joint health in cases of arthritis. However, it is important to always consult a licensed medical practitioner before using any herb for medicinal purposes, and to never change the use of existing prescription drugs without talking to your doctor about it first.
Name clarification: The Japanese name Reishi includes many closely related species. By far the most prevalent is Ganoderma lucidum (Common Reishi or Red Reishi), a species rare in the U.S. but common in South East Asia. The English common name for Ganoderma lucidum is Varnished Conk. In China, its known as Ling Zhi.
Other species frequently referred to as Reishi include: Ganoderma tsugae (Hemlock Reishi, common on Hemlocks in Eastern U.S.), Ganoderma sinense ("Black Reishi), Ganoderma resinaceum (Red Reishi), Ganoderma japonicum (Purple Reishi) and Ganoderma neo-japonicum (no common name or simply Reishi). - 30414
About the Author:
Dr. Rafael works as a natural health researcher and author since 1996, specializing in medicinal mushrooms. Click on Reishi extract for organic mushroom products and free articles on mycomedicinals. Reishi and Arthritis Article References
